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Formula
C16H18N2
MW
238.34
Purity
>97%
Bio Chemical Notes
1-(biphenyl-2-yl) piperazine acts as a 5-HT7 receptor agonist, whose parent drug is LP-211 (HG-0230). Compared to LP-211, it displays higher 5-HT7 receptor affinity (Ki = 1.4 nM, human cloned receptor) and overall better selectivity profile. Ref: JMC DOI: 10.1021/jm3003679