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Abemaciclib (LY2835219)

Name: Abemaciclib (LY2835219)
SKU: AS-10230
Availability: InStock

ID: AS-10230

CAS: 1231929-97-7

ACD NO: MFCD22665744

Product Details

Formula

C27H32F2N8

506.61

Purity

>98%

Solubility (DMSO Mg/MI)

Storage (Powder)

3 Years -20°C

Storage (Solvent)

1 Year -80°C

Indication

Breast Cancer

Mode Of Action

inhibitor

Drug Status

Approved

Target Name

Cyclin-dependent kinase 4 (CDK4)/Cyclin-dependent kinase 6 (CDK6)

Research Area

CANCER

Research Area Sub Group

Anticancer

Pharmacology

ENZYMES

Pharmacology Area Sub Group

Kinase

Abemaciclib is a cell cycle inhibitor selective for CDK4/6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively