![[STAGING] Key Organics](https://staging.keyorganics.net/app/uploads/2026/01/Key-Organics-40th-logo-strip-1.png "Busulfan"){kind=logo}
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Formula
C6H14O6S2
MW
246.3
Purity
>97%
Solubility (DMSO Mg/MI)
40
Storage (Powder)
3 Years -20°C
Storage (Solvent)
1 Year -80°C
Indication
Leukemia
Mode Of Action
alkylation
Drug Status
Approved
Target Name
Human Deoxyribonucleic acid (hDNA)
Research Area
CANCER
Research Area Sub Group
Anticancer
Pharmacology
DNA
Bio Chemical Notes
Busulfan has a selective immunosuppressive effect on bone marrow and has been used in the palliative treatment of chronic myeloid leukemia. Alkylating agent that forms carbonium ions that alkylate DNA, which results in the interference of DNA replication and RNA transcription (leading to cell apoptosis). Ref: Leukemia & Lymphoma. 2012; 53 (5) , 973-981.