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Formula
C13H22ClN3O
MW
271.79
Purity
>97%
Solubility (DMSO Mg/MI)
50
Storage (Powder)
3 Years -20°C
Storage (Solvent)
1 Year -80°C
Indication
N/A
Mode Of Action
blocker
Drug Status
Approved
Target Name
Voltage-gated sodium channel (Nav)
Research Area
CARDIOVASCULAR
Research Area Sub Group
Antiarrhythmic
Pharmacology
ION CHANNELS
Pharmacology Area Sub Group
Sodium Channels
Bio Chemical Notes
Indicated for local or regional anesthesia and treatment of ventricular tachycardia. A sodium channel blocker which stabilizes the neuronal membrane by inhibiting ionic fluxes. Also inhibits DNA methyltransferase and modulates epigenetic regulation of gene expression. Ref: The Journal of Biological Chemistry. 2005; 280; 40749-40756.